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Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model

Hypophosphatasia (HPP) is a rare metabolic bone disorder characterized by low levels of tissue non-specific alkaline phosphatase (TNAP) that causes under-mineralization of the bone, leading to bone deformity and fractures. In addition, patients often present with chronic muscle pain, reduced muscle...

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Detalles Bibliográficos
Autores principales: Pendleton, Emily G., Nichenko, Anna S., Mcfaline-Figueroa, Jennifer, Raymond-Pope, Christiana J., Schifino, Albino G., Pigg, Taylor M., Barrow, Ruth P., Greising, Sarah M., Call, Jarrod A., Mortensen, Luke J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649932/
https://www.ncbi.nlm.nih.gov/pubmed/37958888
http://dx.doi.org/10.3390/ijms242115905