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Novel Mitochondria-Targeted Amphiphilic Aminophosphonium Salts and Lipids Nanoparticles: Synthesis, Antitumor Activity and Toxicity

The creation of mitochondria-targeted vector systems is a new tool for the treatment of socially significant diseases. Phosphonium groups provide targeted delivery of drugs through biological barriers to organelles. For this purpose, a new class of alkyl(diethylAmino)(Phenyl) Phosphonium halides (AP...

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Detalles Bibliográficos
Autores principales: Mironov, Vladimir F., Dimukhametov, Mudaris N., Nemtarev, Andrey V., Pashirova, Tatiana N., Tsepaeva, Olga V., Voloshina, Alexandra D., Vyshtakalyuk, Alexandra B., Litvinov, Igor A., Lyubina, Anna P., Sapunova, Anastasiia S., Abramova, Dinara F., Zobov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649961/
https://www.ncbi.nlm.nih.gov/pubmed/37947686
http://dx.doi.org/10.3390/nano13212840