Solubility and Pharmacokinetic Profile Improvement of Griseofulvin through Supercritical Carbon Dioxide-Assisted Complexation with HP-γ-Cyclodextrin

Since griseofulvin was marketed as a non-polyene antifungal antibiotic drug in 1958, its poor water solubility has been an issue for its wide applications, and over the last sixty years, many attempts have been made to increase its water solubility; however, a significant result has yet to be achiev...

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Detalles Bibliográficos
Autores principales: Ding, Yili, Cui, Wutong, Zhang, Zhiyuan, Ma, Yanzhi, Ding, Charles, Lin, Yikai, Xu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650103/
https://www.ncbi.nlm.nih.gov/pubmed/37959779
http://dx.doi.org/10.3390/molecules28217360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650103/
https://www.ncbi.nlm.nih.gov/pubmed/37959779
http://dx.doi.org/10.3390/molecules28217360

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