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Trans-(±)-TTPG-B Attenuates Cell Cycle Progression and Inhibits Cell Proliferation on Cholangiocarcinoma Cells

This research aimed to determine the target protein and molecular mechanism of trans-(±)-kusunokinin ((±)-KU) derivatives (trans-(±)-ARC and trans-(±)-TTPG-B). Molecular docking was used to predict potential synthesized (±)-KU targets among 22 proteins. The (±)-TTPG-B bound HSP90α better than EC44,...

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Detalles Bibliográficos
Autores principales: Rattanaburee, Thidarath, Chompunud Na Ayudhya, Chompunud, Thongpanchang, Tienthong, Tipmanee, Varomyalin, Graidist, Potchanapond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650166/
https://www.ncbi.nlm.nih.gov/pubmed/37959760
http://dx.doi.org/10.3390/molecules28217342