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PD-L1 and HIF-2α Upregulation in Head and Neck Paragangliomas after Embolization

SIMPLE SUMMARY: In solid tumors, hypoxia activates pathways associated with tumor progression and induces alterations in the immune microenvironment such as the upregulation of programmed cell death-ligand 1 (PD-L1). Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors which a...

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Detalles Bibliográficos
Autores principales: Fischer, Alessa, Maccio, Umberto, Wang, Katharina, Friemel, Juliane, Broglie Daeppen, Martina A., Vetter, Diana, Lehmann, Kuno, Reul, Astrid, Robledo, Mercedes, Hantel, Constanze, Bechmann, Nicole, Pacak, Karel, Zitzmann, Kathrin, Auernhammer, Christoph J., Grossman, Ashley B., Beuschlein, Felix, Nölting, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650267/
https://www.ncbi.nlm.nih.gov/pubmed/37958373
http://dx.doi.org/10.3390/cancers15215199