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Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling
SIMPLE SUMMARY: Multiple myeloma cells mainly proliferate in the bone marrow (BM). Mesenchymal stem cells (MSCs) in the BM of MM patients are tumor supportive and exhibit an inflammatory transcription signature and contribute to drug resistance. Due to their rarity in the BM, downstream functional c...
Autores principales: | Wang, Lei, Yi, Weijun, Ma, Li, Lecea, Emily, Hazlehurst, Lori A., Adjeroh, Donald A., Hu, Gangqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650304/ https://www.ncbi.nlm.nih.gov/pubmed/37958322 http://dx.doi.org/10.3390/cancers15215148 |
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