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Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure

We aimed to investigate the contribution of co-translational protein aggregation to the chemotherapy resistance of tumor cells. Increased co-translational protein aggregation reflects altered translation regulation that may have the potential to buffer transcription under genotoxic stress. As an ind...

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Detalles Bibliográficos
Autores principales: Nagy-Mikó, Bence, Németh-Szatmári, Orsolya, Faragó-Mészáros, Réka, Csókási, Aliz, Bognár, Bence, Ördög, Nóra, Borsos, Barbara N., Majoros, Hajnalka, Ujfaludi, Zsuzsanna, Oláh-Németh, Orsolya, Nikolényi, Aliz, Dobi, Ágnes, Kószó, Renáta, Sántha, Dóra, Lázár, György, Simonka, Zsolt, Paszt, Attila, Ormándi, Katalin, Pankotai, Tibor, Boros, Imre M., Villányi, Zoltán, Vörös, András
Formato: Online Artigo Texto
Idioma:English
Publicado: MDPI 2023
Materias:
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650411/
https://www.ncbi.nlm.nih.gov/pubmed/37958852
http://dx.doi.org/10.3390/ijms242115869