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Amino Acid Derivatives of Ginsenoside AD-2 Induce HepG2 Cell Apoptosis by Affecting the Cytoskeleton

AD-2 (20(R)-dammarane-3β, 12β, 20, 25-tetrol, 25-OH-PPD) was structurally modified to introduce additional amino groups, which can better exert its anti-tumor effects in MCF-7, A549, LoVo, HCT-116, HT -29, and U-87 cell lines. We investigated the cellular activity of 15 different AD-2 amino acid der...

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Detalles Bibliográficos
Autores principales: Lin, Lizhen, Zhao, Yuqing, Wang, Peng, Li, Tao, Liang, Yuhang, Chen, Yu, Meng, Xianyi, Zhang, Yudong, Su, Guangyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650444/
https://www.ncbi.nlm.nih.gov/pubmed/37959819
http://dx.doi.org/10.3390/molecules28217400