Combined Inhibition of UBE2C and PLK1 Reduce Cell Proliferation and Arrest Cell Cycle by Affecting ACLY in Pan-Cancer

Various studies have shown that the cell-cycle-related regulatory proteins UBE2C, PLK1, and BIRC5 promote cell proliferation and migration in different types of cancer. However, there is a lack of in-depth and systematic research on the mechanism of these three as therapeutic targets. In this study,...

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Detalles Bibliográficos
Autores principales: Liang, Keying, Wang, Qian, Qiu, Li, Gong, Xiaocheng, Chen, Zixi, Zhang, Haibo, Ding, Ke, Liu, Yunfei, Wei, Jinfen, Lin, Shudai, Fu, Shuying, Du, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650476/
https://www.ncbi.nlm.nih.gov/pubmed/37958642
http://dx.doi.org/10.3390/ijms242115658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650476/
https://www.ncbi.nlm.nih.gov/pubmed/37958642
http://dx.doi.org/10.3390/ijms242115658

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