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Cholesterol Metabolism in Pancreatic Cancer

SIMPLE SUMMARY: This review delves into metabolic reprogramming in pancreatic cancer and its development, with a special emphasis on the mevalonate pathway, encompassing cholesterol biosynthesis, transport, targeting approaches, and clinical investigations. It describes how cancer cells manipulate c...

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Detalles Bibliográficos
Autores principales: Rebelo, Artur, Kleeff, Jörg, Sunami, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650553/
https://www.ncbi.nlm.nih.gov/pubmed/37958351
http://dx.doi.org/10.3390/cancers15215177