Cargando…

Sorafenib Resistance Contributed by IL7 and MAL2 in Hepatocellular Carcinoma Can Be Overcome by Autophagy-Inducing Stapled Peptides

SIMPLE SUMMARY: Drug resistance remains a major challenge in the treatment of hepatocellular carcinoma (HCC). Our objective was to investigate the genetic mechanisms involved in the development of Sorafenib-associated drug resistance in HCC cells. To achieve this, transposon insertional mutagenesis...

Descripción completa

Detalles Bibliográficos
Autores principales: To, Jeffrey C., Gao, Shan, Li, Xiao-Xiao, Zhao, Yanxiang, Keng, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650575/
https://www.ncbi.nlm.nih.gov/pubmed/37958451
http://dx.doi.org/10.3390/cancers15215280