A New Stereoselective Approach to the Substitution of Allyl Hydroxy Group in para-Mentha-1,2-diol in the Search for New Antiparkinsonian Agents

Two approaches to the synthesis of para-menthene epoxide ((1S,5S,6R)-4) are developed. The first approach includes a reaction between chlorohydrin 7 and NaH in THF. The second involves the formation of epoxide in the reaction of corresponding diacetate 6 with sodium tert-butoxide. One possible mecha...

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Detalles Bibliográficos
Autores principales: Podturkina, Alexandra V., Ardashov, Oleg V., Volcho, Konstantin P., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650740/
https://www.ncbi.nlm.nih.gov/pubmed/37959723
http://dx.doi.org/10.3390/molecules28217303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650740/
https://www.ncbi.nlm.nih.gov/pubmed/37959723
http://dx.doi.org/10.3390/molecules28217303

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