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Synthesis and In Vivo Antiarrhythmic Activity Evaluation of Novel Scutellarein Analogues as Voltage-Gated Nav1.5 and Cav1.2 Channels Blockers

Malignant cardiac arrhythmias with high morbidity and mortality have posed a significant threat to our human health. Scutellarein, a metabolite of Scutellarin which is isolated from Scutellaria altissima L., presents excellent therapeutic effects on cardiovascular diseases and could further be metab...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Wang, Wenping, Cai, Song, Li, Peng, Zhang, Die, Ning, Jinhua, Ke, Jin, Hou, Anguo, Chen, Linyun, Ma, Yunshu, Jin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650756/
https://www.ncbi.nlm.nih.gov/pubmed/37959836
http://dx.doi.org/10.3390/molecules28217417