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Comprehensive Physicochemical Characterization, In Vitro Membrane Permeation, and In Vitro Human Skin Cell Culture of a Novel TOPK Inhibitor, HI-TOPK-032

Nonmelanoma skin cancers (NMSC) are the most common skin cancers, and about 5.4 million people are diagnosed each year in the United States. A newly developed T-lymphokine-activated killer cell-originated protein kinase (TOPK) inhibitor, HI-TOPK-032, is effective in suppressing colon cancer cell gro...

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Detalles Bibliográficos
Autores principales: Eedara, Basanth Babu, Manivannan, Bhagyashree, Alabsi, Wafaa, Sun, Bo, Curiel-Lewandrowski, Clara, Zhang, Tianshun, Bode, Ann M., Mansour, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650786/
https://www.ncbi.nlm.nih.gov/pubmed/37958502
http://dx.doi.org/10.3390/ijms242115515