Cargando…
Comprehensive Physicochemical Characterization, In Vitro Membrane Permeation, and In Vitro Human Skin Cell Culture of a Novel TOPK Inhibitor, HI-TOPK-032
Nonmelanoma skin cancers (NMSC) are the most common skin cancers, and about 5.4 million people are diagnosed each year in the United States. A newly developed T-lymphokine-activated killer cell-originated protein kinase (TOPK) inhibitor, HI-TOPK-032, is effective in suppressing colon cancer cell gro...
Autores principales: | Eedara, Basanth Babu, Manivannan, Bhagyashree, Alabsi, Wafaa, Sun, Bo, Curiel-Lewandrowski, Clara, Zhang, Tianshun, Bode, Ann M., Mansour, Heidi M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650786/ https://www.ncbi.nlm.nih.gov/pubmed/37958502 http://dx.doi.org/10.3390/ijms242115515 |
Ejemplares similares
-
Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery
por: Ruiz, Victor H., et al.
Publicado: (2022) -
Targeting PRPK and TOPK for skin cancer prevention and therapy
por: Roh, Eunmiri, et al.
Publicado: (2018) -
Innovative Rocuronium Bromide Topical Formulation for Targeted Skin Drug Delivery: Design, Comprehensive Characterization, In Vitro 2D/3D Human Cell Culture and Permeation
por: Ruiz, Victor H., et al.
Publicado: (2023) -
Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon
por: Xiao, Juanjuan, et al.
Publicado: (2016) -
PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas
por: Zhu, Kejing, et al.
Publicado: (2022)