Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice

Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the mechanisms underlying nicotine addiction and smoking cessation. Here, we investigate the use of an image-derived arterial input function and...

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Detalles Bibliográficos
Autores principales: Zammit, Matthew, Kao, Chien-Min, Zhang, Hannah J., Tsai, Hsiu-Ming, Holderman, Nathanial, Mitchell, Samuel, Tanios, Eve, Bhuiyan, Mohammed, Freifelder, Richard, Kucharski, Anna, Green, William N., Mukherjee, Jogeshwar, Chen, Chin-Tu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650787/
https://www.ncbi.nlm.nih.gov/pubmed/37958495
http://dx.doi.org/10.3390/ijms242115510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650787/
https://www.ncbi.nlm.nih.gov/pubmed/37958495
http://dx.doi.org/10.3390/ijms242115510

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