Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells

Citrus hassaku extract reportedly activates AMPK. Because this extract contains an abundance of auraptene, we investigated whether pure auraptene activates AMPK and inhibits proliferation using prostate cancer cell lines. Indeed, auraptene inhibited the proliferation and migration of LNCaP cells and...

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Detalles Bibliográficos
Autores principales: Akasaka, Yasuyuki, Hasei, Shun, Ohata, Yukino, Kanna, Machi, Nakatsu, Yusuke, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Ono, Hiraku, Matsubara, Akio, Hinata, Nobuyuki, Asano, Tomoichiro, Yamamotoya, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650886/
https://www.ncbi.nlm.nih.gov/pubmed/37958994
http://dx.doi.org/10.3390/ijms242116011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650886/
https://www.ncbi.nlm.nih.gov/pubmed/37958994
http://dx.doi.org/10.3390/ijms242116011

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