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Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells
Citrus hassaku extract reportedly activates AMPK. Because this extract contains an abundance of auraptene, we investigated whether pure auraptene activates AMPK and inhibits proliferation using prostate cancer cell lines. Indeed, auraptene inhibited the proliferation and migration of LNCaP cells and...
Autores principales: | Akasaka, Yasuyuki, Hasei, Shun, Ohata, Yukino, Kanna, Machi, Nakatsu, Yusuke, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Ono, Hiraku, Matsubara, Akio, Hinata, Nobuyuki, Asano, Tomoichiro, Yamamotoya, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650886/ https://www.ncbi.nlm.nih.gov/pubmed/37958994 http://dx.doi.org/10.3390/ijms242116011 |
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