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The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity

Hepatitis C virus (HCV) exploits the four entry factors CD81, scavenger receptor class B type I (SR-BI, also known as SCARB1), occludin, and claudin-1 as well as the co-factor epidermal growth factor receptor (EGFR) to infect human hepatocytes. Here, we report that the disintegrin and matrix metallo...

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Detalles Bibliográficos
Autores principales: Carriquí-Madroñal, Belén, Sheldon, Julie, Duven, Mara, Stegmann, Cora, Cirksena, Karsten, Wyler, Emanuel, Zapatero-Belinchón, Francisco J., Vondran, Florian W. R., Gerold, Gisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650992/
https://www.ncbi.nlm.nih.gov/pubmed/37967063
http://dx.doi.org/10.1371/journal.ppat.1011759