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Genome-wide identification of notochord enhancers comprising the regulatory landscape of the brachyury locus in mouse

The node and notochord are important signaling centers organizing the dorso-ventral patterning of cells arising from neuro-mesodermal progenitors forming the embryonic body anlage. Owing to the scarcity of notochord progenitors and notochord cells, a comprehensive identification of regulatory elemen...

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Detalles Bibliográficos
Autores principales: Schifferl, Dennis, Scholze-Wittler, Manuela, Villaronga Luque, Alba, Pustet, Milena, Wittler, Lars, Veenvliet, Jesse V., Koch, Frederic, Herrmann, Bernhard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651091/
https://www.ncbi.nlm.nih.gov/pubmed/37882764
http://dx.doi.org/10.1242/dev.202111