Cargando…

Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability

Cyclin D1 is a key regulator of cell cycle progression, which forms a complex with CDK4/6 to regulate G1/S transition during cell cycle progression. Cyclin D1 has been recognized as an oncogene since it was upregulated in several different types of cancers. It is known that the post-translational re...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Ke, Zhang, Ming, Wei, Guizheng, Xiao, Guozhi, Tong, Liping, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651173/
https://www.ncbi.nlm.nih.gov/pubmed/37943017
http://dx.doi.org/10.7554/eLife.80327