The myocardium utilizes a platelet-derived growth factor receptor alpha (Pdgfra)–phosphoinositide 3-kinase (PI3K) signaling cascade to steer toward the midline during zebrafish heart tube formation

Coordinated cell movement is a fundamental process in organ formation. During heart development, bilateral myocardial precursors collectively move toward the midline (cardiac fusion) to form the primitive heart tube. Extrinsic influences such as the adjacent anterior endoderm are known to be require...

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Detalles Bibliográficos
Autores principales: Shrestha, Rabina, McCann, Tess, Saravanan, Harini, Lieberth, Jaret, Koirala, Prashanna, Bloomekatz, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651176/
https://www.ncbi.nlm.nih.gov/pubmed/37921445
http://dx.doi.org/10.7554/eLife.85930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651176/
https://www.ncbi.nlm.nih.gov/pubmed/37921445
http://dx.doi.org/10.7554/eLife.85930

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