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The myocardium utilizes a platelet-derived growth factor receptor alpha (Pdgfra)–phosphoinositide 3-kinase (PI3K) signaling cascade to steer toward the midline during zebrafish heart tube formation
Coordinated cell movement is a fundamental process in organ formation. During heart development, bilateral myocardial precursors collectively move toward the midline (cardiac fusion) to form the primitive heart tube. Extrinsic influences such as the adjacent anterior endoderm are known to be require...
Autores principales: | Shrestha, Rabina, McCann, Tess, Saravanan, Harini, Lieberth, Jaret, Koirala, Prashanna, Bloomekatz, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651176/ https://www.ncbi.nlm.nih.gov/pubmed/37921445 http://dx.doi.org/10.7554/eLife.85930 |
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