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Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs

AIMS: Cardiotoxicity is one major reason why drugs do not enter or are withdrawn from the market. Thus, approaches are required to predict cardiotoxicity with high specificity and sensitivity. Ideally, such methods should be performed within intact cardiac tissue with high relevance for humans and d...

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Detalles Bibliográficos
Autores principales: Shi, Runzhu, Reichardt, Marius, Fiegle, Dominik J, Küpfer, Linda K, Czajka, Titus, Sun, Zhengwu, Salditt, Tim, Dendorfer, Andreas, Seidel, Thomas, Bruegmann, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651213/
https://www.ncbi.nlm.nih.gov/pubmed/37934066
http://dx.doi.org/10.1093/cvr/cvad141