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PROSTATA: a framework for protein stability assessment using transformers

MOTIVATION: Accurate prediction of change in protein stability due to point mutations is an attractive goal that remains unachieved. Despite the high interest in this area, little consideration has been given to the transformer architecture, which is dominant in many fields of machine learning. RESU...

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Detalles Bibliográficos
Autores principales: Umerenkov, Dmitriy, Nikolaev, Fedor, Shashkova, Tatiana I, Strashnov, Pavel V, Sindeeva, Maria, Shevtsov, Andrey, Ivanisenko, Nikita V, Kardymon, Olga L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651431/
https://www.ncbi.nlm.nih.gov/pubmed/37935419
http://dx.doi.org/10.1093/bioinformatics/btad671