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Acryl-3,5-bis(2,4-difluorobenzylidene)-4-piperidone targeting cellular JUN proto-oncogene, AP-1 transcription factor subunit inhibits head and neck squamous cell carcinoma progression

AIM: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with a survival rate below fifty percent. Addressing meager therapeutic options, a series of small molecule inhibitors were screened for antitumor efficacy. The most potent analog, acryl-3,5-bis(2,4-difluo...

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Detalles Bibliográficos
Autores principales: Arnold, Levi, Gomez, Juan Pineda, Barry, Michael, Yap, Marrion, Jackson, Laura, Ly, Thuc, Standing, David, Padhye, Subhash B., Biersack, Bernhard, Anant, Shrikant, Thomas, Sufi Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651473/
https://www.ncbi.nlm.nih.gov/pubmed/38023989
http://dx.doi.org/10.37349/etat.2023.00184