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A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes

Molnupiravir, an antiviral medication widely used against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), acts by inducing mutations in the virus genome during replication. Most random mutations are likely to be deleterious to the virus and many will be lethal; thus, molnupiravir-induc...

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Detalles Bibliográficos
Autores principales: Sanderson, Theo, Hisner, Ryan, Donovan-Banfield, I’ah, Hartman, Hassan, Løchen, Alessandra, Peacock, Thomas P., Ruis, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651478/
https://www.ncbi.nlm.nih.gov/pubmed/37748513
http://dx.doi.org/10.1038/s41586-023-06649-6