Cargando…
m(1)A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
Microsatellite repeat expansions within genes contribute to a number of neurological diseases(1,2). The accumulation of toxic proteins and RNA molecules with repetitive sequences, and/or sequestration of RNA-binding proteins by RNA molecules containing expanded repeats are thought to be important co...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651481/ https://www.ncbi.nlm.nih.gov/pubmed/37938769 http://dx.doi.org/10.1038/s41586-023-06701-5 |