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m(1)A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration
Microsatellite repeat expansions within genes contribute to a number of neurological diseases(1,2). The accumulation of toxic proteins and RNA molecules with repetitive sequences, and/or sequestration of RNA-binding proteins by RNA molecules containing expanded repeats are thought to be important co...
Autores principales: | Sun, Yuxiang, Dai, Hui, Dai, Xiaoxia, Yin, Jiekai, Cui, Yuxiang, Liu, Xiaochuan, Gonzalez, Gwendolyn, Yuan, Jun, Tang, Feng, Wang, Nan, Perlegos, Alexandra E., Bonini, Nancy M., Yang, X. William, Gu, Weifeng, Wang, Yinsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651481/ https://www.ncbi.nlm.nih.gov/pubmed/37938769 http://dx.doi.org/10.1038/s41586-023-06701-5 |
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