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DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathway

Abnormal trophoblast function is associated with diseases such as recurrent spontaneous abortion, pre-eclampsia, and preterm birth, and endangers maternal and fetal health. However, the underlying regulatory mechanisms remain unclear. In this study, we found DOCK1 expression is decreased in the plac...

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Detalles Bibliográficos
Autores principales: Xu, Yichi, Liu, Xiaorui, Zeng, Weihong, Zhu, Yueyue, Dong, Junpeng, Wu, Fan, Chen, Cailian, Sharma, Surendra, Lin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651491/
https://www.ncbi.nlm.nih.gov/pubmed/37967942
http://dx.doi.org/10.26508/lsa.202302247