Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo

Short telomeres are a defining feature of telomere biology disorders (TBDs), including dyskeratosis congenita (DC), for which there is no effective general cure. Patients with TBDs often experience bone marrow failure. NAD, an essential metabolic coenzyme, is decreased in models of DC. Herein, using...

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Detalles Bibliográficos
Autores principales: Stock, Amanda J., Ayyar, Saipriya, Kashyap, Amogh, Wang, Yunong, Yanai, Hagai, Starost, Matthew F., Tanaka-Yano, Mayuri, Bodogai, Monica, Sun, Chongkui, Wang, Yajun, Gong, Yi, Puligilla, Chandrakala, Fang, Evandro F., Bohr, Vilhelm A., Liu, Yie, Beerman, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651621/
https://www.ncbi.nlm.nih.gov/pubmed/36826621
http://dx.doi.org/10.1007/s11357-023-00752-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651621/
https://www.ncbi.nlm.nih.gov/pubmed/36826621
http://dx.doi.org/10.1007/s11357-023-00752-2

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