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Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction

Dietary sulfur amino acid restriction (SAAR) protects against diet-induced obesity, extends healthspan, and coincides with an overall reduction in hepatic protein synthesis. To explore the underpinnings of SAAR-induced slowed growth and its impact on liver metabolism and proteostasis, we resolved ch...

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Detalles Bibliográficos
Autores principales: Jonsson, William O., Borowik, Agnieszka K., Pranay, Atul, Kinter, Michael T., Mirek, Emily T., Levy, Jordan L., Snyder, Elizabeth M., Miller, Benjamin F., Anthony, Tracy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651627/
https://www.ncbi.nlm.nih.gov/pubmed/36976488
http://dx.doi.org/10.1007/s11357-023-00758-w