Physiologically based absorption modeling to predict the bioequivalence of two cilostazol formulations

In vivo pharmacokinetic simulations and virtual bioequivalence (BE) evaluation of cilostazol have not yet been described for humans. Here, we successfully developed a physiologically based absorption model to simulate plasma concentrations of cilostazol. In addition, virtual population simulations i...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Zhao, Pengfei, Luo, Ting, Yang, Dandan, Jiang, Qianqian, Chen, Jinliang, Lou, Honggang, Ruan, Zourong, Jiang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651633/
https://www.ncbi.nlm.nih.gov/pubmed/37718502
http://dx.doi.org/10.1111/cts.13633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651633/
https://www.ncbi.nlm.nih.gov/pubmed/37718502
http://dx.doi.org/10.1111/cts.13633

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