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Reconsideration of the current models of estimated kidney function‐based drug dose adjustment in older adults: The role of biological age

Human lifespan has increased from a median of 46.5 years in 1950 to 71.7 years in 2022. As people age, one of the inevitable consequences is a decline in kidney function and glomerular filtration rate (GFR) which can have direct or indirect effects on the pharmacokinetic and pharmacodynamic profiles...

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Detalles Bibliográficos
Autores principales: Alikhani, Radin, Pai, Manjunath P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651638/
https://www.ncbi.nlm.nih.gov/pubmed/37702349
http://dx.doi.org/10.1111/cts.13643