DLX2 promotes osteosarcoma epithelial-mesenchymal transition and doxorubicin resistance by enhancing HOXC8-CDH2 axis

Metastasis and doxorubicin resistance are challenges in the clinical diagnosis and treatment of osteosarcoma, the mechanisms underlying these phenomena remain unclear. In this study, we found that DLX2 is highly expressed in metastatic osteosarcoma and is closely related to clinical prognosis. Knock...

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Detalles Bibliográficos
Autores principales: Zhang, Boya, Du, Xinhui, Fan, Yichao, Qu, Guoxin, Pang, Lon Kai, Zhao, Ruiying, Yao, Weitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651674/
https://www.ncbi.nlm.nih.gov/pubmed/38026218
http://dx.doi.org/10.1016/j.isci.2023.108272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651674/
https://www.ncbi.nlm.nih.gov/pubmed/38026218
http://dx.doi.org/10.1016/j.isci.2023.108272

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