A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice

Changes in genomic structures underlie phenotypic diversification in organisms. Amino acid-changing mutations affect pleiotropic functions of proteins, although little is known about how mutated proteins are adapted in existing developmental programs. Here we investigate the biological effects of a...

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Detalles Bibliográficos
Autores principales: Agata, Ako, Ohtsuka, Satoshi, Noji, Ryota, Gotoh, Hitoshi, Ono, Katsuhiko, Nomura, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651735/
https://www.ncbi.nlm.nih.gov/pubmed/38020913
http://dx.doi.org/10.3389/fcell.2023.1247361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651735/
https://www.ncbi.nlm.nih.gov/pubmed/38020913
http://dx.doi.org/10.3389/fcell.2023.1247361

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