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A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice
Changes in genomic structures underlie phenotypic diversification in organisms. Amino acid-changing mutations affect pleiotropic functions of proteins, although little is known about how mutated proteins are adapted in existing developmental programs. Here we investigate the biological effects of a...
Autores principales: | Agata, Ako, Ohtsuka, Satoshi, Noji, Ryota, Gotoh, Hitoshi, Ono, Katsuhiko, Nomura, Tadashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651735/ https://www.ncbi.nlm.nih.gov/pubmed/38020913 http://dx.doi.org/10.3389/fcell.2023.1247361 |
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