NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on an MRD-based protocol

We compared minimal/measurable residual disease (MRD) levels evaluated by routinely used real-time quantitative polymerase chain reaction (qPCR) patient-specific assays and by next-generation sequencing (NGS) approach in 780 immunoglobulin (IG) and T-cell receptor (TR) markers in 432 children with B...

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Detalles Bibliográficos
Autores principales: Svaton, Michael, Skotnicova, Aneta, Reznickova, Leona, Rennerova, Andrea, Valova, Tatana, Kotrova, Michaela, van der Velden, Vincent H. J., Brüggemann, Monika, Darzentas, Nikos, Langerak, Anton W., Zuna, Jan, Stary, Jan, Trka, Jan, Fronkova, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651772/
https://www.ncbi.nlm.nih.gov/pubmed/36240445
http://dx.doi.org/10.1182/blood.2022017003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651772/
https://www.ncbi.nlm.nih.gov/pubmed/36240445
http://dx.doi.org/10.1182/blood.2022017003

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