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A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease

Acute graft-versus-host disease (aGVHD) is an immune cell‒driven, potentially lethal complication of allogeneic hematopoietic stem cell transplantation affecting diverse organs, including the skin, liver, and gastrointestinal (GI) tract. We applied mass cytometry (CyTOF) to dissect circulating myelo...

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Detalles Bibliográficos
Autores principales: van Halteren, Astrid G. S., Suwandi, Jessica S., Tuit, Sander, Borst, Jelske, Laban, Sandra, Tsonaka, Roula, Struijk, Ada, Wiekmeijer, Anna-Sophia, van Pel, Melissa, Roep, Bart O., Zwaginga, Jaap Jan, Lankester, Arjan C., Schepers, Koen, van Tol, Maarten J. D., Fibbe, Willem E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651784/
https://www.ncbi.nlm.nih.gov/pubmed/36044666
http://dx.doi.org/10.1182/blood.2022015734