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Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype

FOXO3 is a ubiquitous transcription factor expressed in response to cellular stress caused by nutrient deprivation, inflammatory cytokines, reactive oxygen species, radiation, hypoxia, and other factors. We showed previously that the association of inherited FOXO3 variants with longevity was the res...

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Detalles Bibliográficos
Autores principales: Donlon, Timothy A., Morris, Brian J., Chen, Randi, Lim, Eunjung, Morgen, Eric K., Fortney, Kristen, Shah, Naisha, Masaki, Kamal H., Willcox, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651822/
https://www.ncbi.nlm.nih.gov/pubmed/36881352
http://dx.doi.org/10.1007/s11357-023-00740-6