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M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation

Glutamine synthetases (GS) play central roles in cellular nitrogen assimilation. Although GS active-site formation requires the oligomerization of just two GS subunits, all GS form large, multi-oligomeric machines. Here we describe a structural dissection of the archaeal Methanosarcina mazei (Mm) GS...

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Detalles Bibliográficos
Autores principales: Schumacher, Maria A., Salinas, Raul, Travis, Brady A., Singh, Rajiv Ranjan, Lent, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651883/
https://www.ncbi.nlm.nih.gov/pubmed/37968329
http://dx.doi.org/10.1038/s41467-023-43243-w