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Liquid-liquid phase separation in DNA double-strand breaks repair

DNA double-strand breaks (DSBs) are the fatal type of DNA damage mostly induced by exposure genome to ionizing radiation or genotoxic chemicals. DSBs are mainly repaired by homologous recombination (HR) and nonhomologous end joining (NHEJ). To repair DSBs, a large amount of DNA repair factors was ob...

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Detalles Bibliográficos
Autores principales: Wang, Yun-Long, Zhao, Wan-Wen, Shi, Jie, Wan, Xiang-Bo, Zheng, Jian, Fan, Xin-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651886/
https://www.ncbi.nlm.nih.gov/pubmed/37968256
http://dx.doi.org/10.1038/s41419-023-06267-0