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Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS

Lysophosphatidic acid (LPA) is an active phospholipid signaling molecule that binds to six specific G protein-coupled receptors (LPA(1-6)) on the cell surface and exerts a variety of biological functions, including cell migration and proliferation, morphological changes, and anti-apoptosis. The earl...

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Detalles Bibliográficos
Autores principales: An, Xiaogang, Zhong, Cuiping, Han, Bang, Chen, Erfang, Zhu, Qingwen, Yang, Yang, Li, Rui, Yang, Runqin, Zha, Dingjun, Han, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651903/
https://www.ncbi.nlm.nih.gov/pubmed/37968255
http://dx.doi.org/10.1038/s41420-023-01706-5