Polysorbate 80 surface modified SLNs of formoterol suppress SNCA gene and mitochondrial oxidative stress in mice model of Parkinson’s disease

The present study hypothesises that the selective brain β2 receptor activation through β2-adrenoreceptor agonist (β2ARA), Formoterol (FMT), suppresses SNCA gene expression, a pathological hallmark of Parkinson’s disease (PD) in brain. Further, it is also hypothesized that brain targeted delivery of...

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Detalles Bibliográficos
Autores principales: Sola, Piyong, Garikapati, Kusuma Kumari, Krishnamurthy, Praveen Thaggikuppe, Kumari, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651909/
https://www.ncbi.nlm.nih.gov/pubmed/37968340
http://dx.doi.org/10.1038/s41598-023-46511-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651909/
https://www.ncbi.nlm.nih.gov/pubmed/37968340
http://dx.doi.org/10.1038/s41598-023-46511-3

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