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Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease

Mucosal-associated invariant T (MAIT) cells have been implicated in various inflammatory diseases of barrier organs, but so far, their role in kidney disease is unclear. Here we report that MAIT cells that recognize their prototypical ligand, the vitamin B2 intermediate 5-OP-RU presented by MR1, res...

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Detalles Bibliográficos
Autores principales: Gnirck, Ann-Christin, Philipp, Marie-Sophie, Waterhölter, Alex, Wunderlich, Malte, Shaikh, Nikhat, Adamiak, Virginia, Henneken, Lena, Kautz, Tobias, Xiong, Tingting, Klaus, Daniela, Tomczyk, Pascal, Al-Bahra, Mohamad M., Menche, Dirk, Walkenhorst, Mark, Lantz, Olivier, Willing, Anne, Friese, Manuel A., Huber, Tobias B., Krebs, Christian F., Panzer, Ulf, Kurts, Christian, Turner, Jan-Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651937/
https://www.ncbi.nlm.nih.gov/pubmed/37968302
http://dx.doi.org/10.1038/s41467-023-43269-0