Cargando…

Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice

Opioid-dependent immune-mediated analgesic effects have been broadly reported upon inflammation. In preclinical mouse models of intestinal inflammatory diseases, the local release of enkephalins (endogenous opioids) by colitogenic T lymphocytes alleviate inflammation-induced pain by down-modulating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mas-Orea, Xavier, Rey, Lea, Battut, Louise, Bories, Cyrielle, Petitfils, Camille, Abot, Anne, Gheziel, Nadine, Wemelle, Eve, Blanpied, Catherine, Motta, Jean-Paul, Knauf, Claude, Barreau, Frederick, Espinosa, Eric, Aloulou, Meryem, Cenac, Nicolas, Serino, Matteo, Mouledous, Lionel, Fazilleau, Nicolas, Dietrich, Gilles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652007/ https://www.ncbi.nlm.nih.gov/pubmed/37968381 http://dx.doi.org/10.1038/s42003-023-05542-2

Ejemplares similares

Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice
por: Mas-Orea, Xavier, et al.
Publicado: (2021)

Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis
por: Mas-Orea, Xavier, et al.
Publicado: (2022)

Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions
por: Fazilleau, Nicolas, et al.
Publicado: (2018)

Regulation of B cell responses by distinct populations of CD4 T cells
por: Aloulou, Meryem, et al.
Publicado: (2019)

Glucose Stimulates Gut Motility in Fasted and Fed Conditions: Potential Involvement of a Nitric Oxide Pathway
por: Wemelle, Eve, et al.
Publicado: (2022)

Interconnected subsets of memory follicular helper T cells have different effector functions
por: Asrir, Assia, et al.
Publicado: (2017)

Assessing GFR With Proenkephalin
por: Beunders, Remi, et al.
Publicado: (2023)

Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice
por: Abot, Anne, et al.
Publicado: (2021)

Camu-Camu Reduces Obesity and Improves Diabetic Profiles of Obese and Diabetic Mice: A Dose-Ranging Study
por: Abot, Anne, et al.
Publicado: (2022)

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells
por: Aloulou, Meryem, et al.
Publicado: (2016)

A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage
por: Argenty, Jérémy, et al.
Publicado: (2022)

Targeting of frog prodermorphin to the regulated secretory pathway by fusion to proenkephalin
Publicado: (1991)

Proenkephalin A as Potential Prognostic Biomarker in Acute Ischemic Stroke
por: Shafieesabet, Azadeh, et al.
Publicado: (2020)

Proenkephalin Decreases in Cerebrospinal Fluid with Symptom Progression of Huntington's Disease
por: Niemela, Valter, et al.
Publicado: (2020)

Prodynorphin and Proenkephalin in Cerebrospinal Fluid of Sporadic Creutzfeldt–Jakob Disease
por: Abu-Rumeileh, Samir, et al.
Publicado: (2022)

Proenkephalin is a nuclear protein responsive to growth arrest and differentiation signals
Publicado: (1995)

Plasma Proenkephalin and Poor Long-Term Outcome in Renal Transplant Recipients
por: Kieneker, Lyanne M., et al.
Publicado: (2017)

Proenkephalin A and bioactive adrenomedullin are useful for risk prognostication in cardiac surgery
por: Hill, Aileen, et al.
Publicado: (2023)

High Hydrostatic Pressure Processing of Human Milk Increases Apelin and GLP-1 Contents to Modulate Gut Contraction and Glucose Metabolism in Mice Compared to Holder Pasteurization
por: Wemelle, Eve, et al.
Publicado: (2022)

Bioactive adrenomedullin, proenkephalin A and clinical outcomes in an acute heart failure setting
por: Molvin, John, et al.
Publicado: (2019)

High expression of proenkephalin is associated with favorable outcomes in patients with gastrointestinal stromal tumors
por: Tang, Defeng, et al.
Publicado: (2019)

Proenkephalin Derived Peptides Are Involved in the Modulation of Mitochondrial Respiratory Control During Epileptogenesis
por: Burtscher, Johannes, et al.
Publicado: (2018)

Proenkephalin Predicts Organ Failure, Renal Replacement Therapy, and Mortality in Patients With Sepsis
por: Kim, Hanah, et al.
Publicado: (2020)

Proenkephalin A Adds No Incremental Prognostic Value After Acute Ischemic Stroke
por: Gruber, Philipp, et al.
Publicado: (2020)

Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington’s and Parkinson’s disease
por: Barschke, Peggy, et al.
Publicado: (2022)

Impact of Intestinal Peptides on the Enteric Nervous System: Novel Approaches to Control Glucose Metabolism and Food Intake
por: Abot, Anne, et al.
Publicado: (2018)

Proenkephalin and prognosis in heart failure with preserved ejection fraction: a GREAT network study
por: Kanagala, Prathap, et al.
Publicado: (2019)

Proenkephalin, Neutrophil Gelatinase-Associated Lipocalin, and Estimated Glomerular Filtration Rates in Patients With Sepsis
por: Kim, Hanah, et al.
Publicado: (2017)

Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients
por: Beunders, Remi, et al.
Publicado: (2020)

Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration
por: Liu, Chi, et al.
Publicado: (2023)

Epithelial expression and function of trypsin-3 in irritable bowel syndrome
por: Rolland-Fourcade, Claire, et al.
Publicado: (2017)

Central Effects of Beta-Blockers May Be Due to Nitric Oxide and Hydrogen Peroxide Release Independently of Their Ability to Cross the Blood-Brain Barrier
por: Laurens, Claire, et al.
Publicado: (2019)

In Vivo Assessment of Antioxidant Potential of Human Milk Treated by Holder Pasteurization or High Hydrostatic Pressure Processing: A Preliminary Study on Intestinal and Hepatic Markers in Adult Mice
por: Wemelle, Eve, et al.
Publicado: (2022)

Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats
por: Cadet, Jean Lud, et al.
Publicado: (2016)

The opposing action of stromal cell proenkephalin and stem cell transcription factors in prostate cancer differentiation
por: Liu, Alvin Y.
Publicado: (2021)

Roles of the ubiquitin proteasome system in the effects of drugs of abuse
por: Massaly, Nicolas, et al.
Publicado: (2015)

House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation
por: Serhan, Nadine, et al.
Publicado: (2019)

Maternal prebiotic supplementation impacts colitis development in offspring mice
por: Lê, Amélie, et al.
Publicado: (2023)

Dysosmobacter welbionis effects on glucose, lipid, and energy metabolism are associated with specific bioactive lipids
por: Moens de Hase, Emilie, et al.
Publicado: (2023)

Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression
por: Schiltz, Craig A, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_bflr6tevtdg8rmrofuop3f5hhd