Single cell dynamics of tumor specificity vs bystander activity in CD8(+) T cells define the diverse immune landscapes in colorectal cancer

CD8(+) T cell activation via immune checkpoint blockade (ICB) is successful in microsatellite instable (MSI) colorectal cancer (CRC) patients. By comparison, the success of immunotherapy against microsatellite stable (MSS) CRC is limited. Little is known about the most critical features of CRC CD8(+...

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Detalles Bibliográficos
Autores principales: Borràs, Daniel Morales, Verbandt, Sara, Ausserhofer, Markus, Sturm, Gregor, Lim, Jinyeong, Verge, Gil Arasa, Vanmeerbeek, Isaure, Laureano, Raquel S., Govaerts, Jannes, Sprooten, Jenny, Hong, Yourae, Wall, Rebecca, De Hertogh, Gert, Sagaert, Xavier, Bislenghi, Gabriele, D’Hoore, André, Wolthuis, Albert, Finotello, Francesca, Park, Woong-Yang, Naulaerts, Stefan, Tejpar, Sabine, Garg, Abhishek D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652011/
https://www.ncbi.nlm.nih.gov/pubmed/37968259
http://dx.doi.org/10.1038/s41421-023-00605-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652011/
https://www.ncbi.nlm.nih.gov/pubmed/37968259
http://dx.doi.org/10.1038/s41421-023-00605-4

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