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Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

Spinal muscular atrophy is an autosomal recessive neuromuscular disease caused by mutations in the multifunctional protein Survival of Motor Neuron, or SMN. Within the nucleus, SMN localizes to Cajal bodies, which are associated with nucleoli, nuclear organelles dedicated to the first steps of ribos...

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Detalles Bibliográficos
Autores principales: Musawi, Shaqraa, Donnio, Lise-Marie, Zhao, Zehui, Magnani, Charlène, Rassinoux, Phoebe, Binda, Olivier, Huang, Jianbo, Jacquier, Arnaud, Coudert, Laurent, Lomonte, Patrick, Martinat, Cécile, Schaeffer, Laurent, Mottet, Denis, Côté, Jocelyn, Mari, Pierre-Olivier, Giglia-Mari, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652021/
https://www.ncbi.nlm.nih.gov/pubmed/37968267
http://dx.doi.org/10.1038/s41467-023-42390-4