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The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling

In vertebrates, the earliest hematopoietic stem and progenitor cells (HSPCs) are derived from a subset of specialized endothelial cells, hemogenic endothelial cells, in the aorta-gonad-mesonephros region through endothelial-to-hematopoietic transition. HSPC generation is efficiently and accurately r...

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Detalles Bibliográficos
Autores principales: Li, Ying, Li, Can, Liu, Mengyao, Liu, Shicheng, Liu, Feng, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652045/
https://www.ncbi.nlm.nih.gov/pubmed/37874038
http://dx.doi.org/10.1242/dev.201890