Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells

The amino acid L-proline exhibits growth factor-like properties during development – from improving blastocyst development to driving neurogenesis in vitro. Addition of 400 μM L-proline to self-renewal medium drives naïve mouse embryonic stem cells (ESCs) to early primitive ectoderm-like (EPL) cells...

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Detalles Bibliográficos
Autores principales: Glover, Hannah J., Holliday, Holly, Shparberg, Rachel A., Winkler, David, Day, Margot, Morris, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652046/
https://www.ncbi.nlm.nih.gov/pubmed/37823343
http://dx.doi.org/10.1242/dev.201704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652046/
https://www.ncbi.nlm.nih.gov/pubmed/37823343
http://dx.doi.org/10.1242/dev.201704

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